Early Detection Research Network (EDRN)

The Early Detection Research Network (EDRN) is a collaborative network focused on the early detection of various cancers through biomarker validation, imaging, and data coordination. It supports multiple cancer types including breast, lung, ovarian, pancreatic, and prostate cancers. The network involves multiple research centers and institutions across the United States, aiming to improve early cancer detection, reduce overdiagnosis, and enhance personalized cancer care. It involves multiple Biomarker Characterization Centers (BCCs) and Clinical Validation Centers (CVCs) across the United States, working on cancers including lung, ovary, prostate, breast, colon, esophagus, head and neck, and liver. The network aims to improve early cancer detection through biomarker research, clinical trials, and validation studies, leveraging multidisciplinary expertise and advanced technologies. The EDRN Biomarker Characterization Centers (BCC) focus on the early detection of various cancers including lung, ovary, prostate, breast, colon, and esophagus through biomarker discovery, development, and validation. They aim to improve cancer management by developing sensitive and specific assays for early diagnosis and risk stratification, often using minimally invasive methods. The centers collaborate with academic and industry partners and utilize advanced technologies such as DNA methylation detection, gene expression profiling, proteogenomics, and microbiome analysis. The network supports diverse populations and integrates multidisciplinary expertise to translate discoveries into clinical diagnostics.